Buchiglass – chemReactor CR – high-performance reactor system

High-performance reactor systems for API synthesis, small scale production and pilot plant applications
A clean-room setup and other materials are available to meet your specific process requirements.

Performance and reliability are key issues in the explosion proof design of Buchi glass reaction systems. The inert materials allow safe processing in a inert atmosphere of a wide range of solvents and acids in a completely sealed glass reaction system under full vacuum. Multiple chemical reaction steps are performed safely in the same setup.

Technical Specifications

Glass, glass-lined steel reactor:	15, 30, 60, 100, 160, 250 liter
Pressure:	-1.0 (FV) to +0.5 bar
Temperature:	-60 °C (-90 °C) to +200 °C
Material:	Borosilicate glass 3.3, glass-lined steel, PTFE, PFA, tantalum

Key Features

Standard package

• Jacketed full glass / glass-lined steel reactor
• Multipurpose glass distillation overhead
• Stainless steel frame, supporting flexible glass superstructure
• ATEX Zone 1 (0), CE, cGMP
• CIP capable
• FDA conform, highly corrosion resistant
• Complete documentation

Standard options

• Reactor lift for easy opening (vessel cleaning)
• Sampling device
• pH monitoring and control
• Gas introduction (Nitrogen purging and active gas)
• Vacuum / exhaust piping
• Additional feeders / receivers
• Solid feeding
• Cryogenic vessel for low temperature chemistry (-90 °C)
• In special glass lining or Hastelloy® C22
• Mixed systems with pressure reactor and vacuum distillation
• IQ, OQ, PQ

Typical applications

• Chemical synthesis
• Peptide production
• Extraction / evaporation
• Process development
• Purification / crystallization
• Cryogenic reactions
• Separation
• Scale-up
• API manufacturing
• Pilot plant / kilo lab