This gene codes for one of six actin proteins, playing a crucial role in cell movement, structure, and signaling. It’s a key component of the contractile apparatus and is linked to Baraitser-Winter syndrome 1, causing intellectual disability and unique facial features. Many similar gene copies exist in the human genome.

The DRX analyzers combine liquid handling, chip management and data capture for switchSENSE® measurements. Bespoke electronics manage the electrical actuation of biomolecules on the biochip and measurement of molecular dynamics via time-correlated single photon counting.

The double color DRX2 analyzer offers the simultaneous measurement of two different species of probes on the same biochip electrode. Each sensor spot carries two nanolever sequences, one with a red tag, and one with a green. 

Microcalorimeters for characterization of biomolecular stability and interactions

MicroCal microcalorimeters are powerful, analytical tools used to study biological systems. These include interactions between molecules as well as changes in conformation such as protein unfolding. The technique is very convenient requiring only minimal assay development and NO labelling. The range includes both Differential Scanning and Isothermal Titration calorimetry.