TA Instruments – RS-DSC
The TA Instruments RS-DSC (Rapid Screening Differential Scanning Calorimeter) is an advanced thermal analysis instrument designed for high-throughput thermal stability testing in biologic drug development. It offers precise and efficient measurement of biomolecule stability, enabling researchers to ensure product quality and accelerate development timelines. Tailored for high-concentration biologic formulations, it addresses the specific needs of antibody drugs and engineered proteins.
Technical Specifications
TA Instruments RS-DSC | |
Cell Geometry | Disposable microfluidic |
Cell Material | Glass |
Sample Format | MFC (Micro Fluidic Chips) |
Working cell volume | 11 µL |
Sample Capacity | 24 MFCs |
Typical Sample Concentration | 20 mg/mL – 330+ mg/mL IgG (protein dependent)1 |
Sample throughput | > 96 samples/day |
Temperature Range | 20-100 °C |
Temperature Scan Rate | 1 or 2 °C/min |
Temperature accuracy | ± 0.2 °C (across all calorimeters); ± 0.1 °C reproducibility2 |
1Using lysozyme in 0.1 M glycine buffer at pH 2.5 or IgG in PBS at pH 7.4 at 1 °C/min 2 Using DPPC in water at pH 7 at 1 °C/min |
TA Instruments RS-DSC
Brand
TA instruments provides innovative material characterization instruments that are widely used for research, analysis, and quality control in the evaluation of physical properties. We are the world’s leading supplier of thermal analysis, rheology, and microcalorimetry instruments, and our product areas have expanded to include thermal conductivity & diffusivity, dilatometry, rubber testing, and dynamic mechanical characterization.
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