Corning – Supplements and Reagents – Growth Factors and Cytokines
The Corning portfolio of cytokines, growth factors, and media supplementation offers a wide array of proteins that result in proliferation or differentiation of the affected cells. Corning offers a broad range of other media growth supplements. Some products are specific to cell type, such as SMC4 (for iPSCs) and T-Cell culture supplement (for T-cells), while other products promote proliferation in a wide variety of cell types. Reducing serum use is made easy with products such as ITS and Corning Nu-Serum™.
Growth factors are proteins that bind to receptors found on the surface of non-hematopoietic cells. Each family of growth factors affect specific cell types (i.e., nerve growth factors (NGFs) affect neuronal cell types, and epidermal growth factors (EGFs) affect epithelial cell types).
Cytokines are a class of signaling molecules or intercellular mediators (proteins, peptides, and glycoproteins) that primarily affect cells of the immune system. However, they can affect various cell types outside of the immune system. Unlike classical hormones, cytokines are produced by a number of tissue or cell types rather than by specialized glands. The effects of cytokines on cells can yield different outcomes, including cell proliferation, chemotaxis, and cell death.
Cytokines and growth factors are similar in their structure and mechanism of action. Both bind and initiate signaling pathways, and many share several intracellular signaling components.
Key Features
- Vialed, highly purified growth factors with high biological activity
- Broad range of highly purified natural and recombinant lymphokines
- Enriched culture supplements to be reconstituted/added in the medium of your choice
- Propagate your cells under more defined serum-reduced or serum-free conditions
Available Products
Corning® Growth Factor
The Corning portfolio of cytokines, growth factors, and media supplementation offers a wide array of proteins that result in proliferation or differentiation of the affected cells.
- Vialed, highly purified growth factors with high biological activity
- Broad range of highly purified natural and recombinant lymphokines
- Enriched culture supplements to be reconstituted/added in the medium of your choice
- Propagate your cells under more defined serum-reduced or serum-free conditions
Growth factors are proteins that bind to receptors found on the surface of non-hematopoietic cells. Each family of growth factors affect specific cell types, e.g., nerve growth factors (NGF) affect nerve cell types, and epidermal growth factors (EGF) affect epithelial cell types.
Corning offers a range of growth factors that are derived from different species, both natural and recombinant. These growth factors have been used to promote long-term proliferation in cell culture and to induce cell differentiation in a variety of cell types under serum-free or reduced serum conditions.
Technical Specifications
| Product Number | Product Name | Qty./Pk | Qty./Cs | Brand | Unit Size |
| 354001 | Corning® Epidermal Growth Factor (EGF), Mouse Natural (Culture Grade), 100µg, 1/Pack | 1 / Pk | 1 / Ea | Corning® | per each |
| 354010 | Corning® Epidermal Growth Factor (EGF), Mouse Natural (Receptor Grade), 100µg, 1/Pack | 1 / Pk | 1 / Ea | Corning® | per each |
| 354039 | Corning® Transforming Growth Factor-b (TGF-b), Human Natural, 1µg, 1/Pack | 1 / Pk | 1 / Ea | Corning® | per each |
| 354052 | Corning® Epidermal Growth Factor (EGF), Human Recombinant, 100µg, 1/Pack | 1 / Pk | 1 / Ea | Corning® | per each |
| 354060 | Corning® Basic Fibroblast Growth Factors (bFGF), Human Recombinant, 10µg, 1/Pack | 1 / Pk | 1 / Ea | Corning® | per each |
| 356001 | Corning® Epidermal Growth Factor (EGF), Mouse Natural (Culture Grade), 1 mg, 100µg/Container, 10/Pack | 1 / Pk | 1 / Ea | Corning® | per each |
| 356010 | Corning® Epidermal Growth Factor (EGF), Mouse Natural (Receptor Grade), 500µg, 100µg/Container, 5/Pack | 1 / Pk | 1 / Ea | Corning® | per each |
| 356039 | Corning® Transforming Growth Factor-b (TGF-b), Human Natural, 5µg, 1µg/Container, 5/Pack | 1 / Pk | 1 / Ea | Corning® | per each |
| 3.56E+05 | Corning® Transforming Growth Factor-b (TGF-b), Human Natural, 10µg, 2µg/Container, 5/Pack | 1 / Pk | 1 / Ea | Corning® | per each |
| 356052 | Corning® Epidermal Growth Factor (EGF), Human Recombinant, 1 mg, 100µg/Container, 10/Pack | 1 / Pk | 1 / Ea | Corning® | per each |
| 356060 | Corning® Basic Fibroblast Growth Factors (bFGF), Human Recombinant, 50µg, 5µg/Container, 10/Pack | 1 / Pk | 1 / Ea | Corning® | per each |
| 356061 | Corning® Basic Fibroblast Growth Factors (bFGF), Human Recombinant, 100µg, 10µg/Container, 10/Pack | 1 / Pk | 1 / Ea | Corning® | per each |
Corning® Cytokines
The Corning portfolio of cytokines, growth factors, and media supplementation offers a wide array of proteins that result in proliferation or differentiation of the affected cells.
- Vialed, highly purified growth factors with high biological activity
- Broad range of highly purified natural and recombinant lymphokines
- Enriched culture supplements to be reconstituted/added in the medium of your choice
- Propagate your cells under more defined serum-reduced or serum-free conditions
Cytokines are a class of signaling molecules or intercellular mediators (proteins, peptides, and glycoproteins) that primarily affect cells of the immune system; however they can affect various cell types outside of the immune system. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. The effects of cytokines on cells can yield different outcomes. Some cytokines cause cell proliferation, while others may cause chemotaxis between cell types, and others can even cause cell death. Cytokines and growth factors are similar in their structure and mechanism of action. Both bind and initiate signaling pathways and many share several intracellular signaling components.
Corning offers a range of cytokines and glycoproteins that are derived from different species. These cytokines have been used to promote long-term proliferation in cell culture and to induce cell-mediated immune responses in a variety of cell types.
Technical Specifications
| Product Number | Product Name | Qty./Pk | Qty./Cs | Brand | Unit Size |
| 354040 | Corning® IL-3 Culture Supplement, Mouse, 25 mL, 1/Pack | 1 / Pk | 1 / Ea | Corning® | per each |
| 354043 | Corning® Interleukin-2 (IL-2), Human Recombinant, 10,000 BRMP Units, 1/Pack | 1 / Pk | 1 / Ea | Corning® | per each |
| 356043 | Corning® Interleukin-2 (IL-2), Human Recombinant, 50,000 BRMP Units, 1/Pack | 1 / Pk | 1 / Ea | Corning® | per each |
Corning® Other Media Growth Supplements
The Corning portfolio of cytokines, growth factors, and media supplementation offers a wide array of proteins that result in proliferation or differentiation of the affected cells.
- Vialed, highly purified growth factors with high biological activity
- Broad range of highly purified natural and recombinant lymphokines
- Enriched culture supplements to be reconstituted/added in the medium of your choice
- Propagate your cells under more defined serum-reduced or serum-free conditions
Corning offers a broad range of other media growth supplements. Some products are specific to cell type, such as SMC4 (for iPSCs) and T-Cell culture supplement (for T-cells), while other products promote proliferation in a wide variety of cell types. Reducing serum use is made easy with products such as ITS and Corning Nu-Serum™.
Technical Specifications
| Product Number | Product Name | Qty./Pk | Qty./Cs | Brand | Unit Size |
| 354006 | Corning® Endothelial Cell Growth Supplement (ECGS), 15mg, 1/Pack | 1 / Pk | 1 / Ea | Corning® | per each |
| 354115 | Corning® T-Cell Culture Supplement with ConA (IL-2 Culture Supplement), Rat, 100 mL, 1/Pack | 1 / Pk | 1 / Ea | Corning® | per each |
| 354123 | Corning® Bovine Pituitary Extract (BPE), 15 mg, 1/Pack | 1 / Pk | 1 / Ea | Corning® | per each |
| 354350 | Corning® ITS Premix Universal Culture Supplement, 20 mL, 1/Pack | 1 / Pk | 1 / Ea | Corning® | per each |
| 354351 | Corning® ITS Premix Universal Culture Supplement, 5 mL, 1/Pack | 1 / Pk | 1 / Ea | Corning® | per each |
| 354352 | Corning® ITS+ Premix Universal Culture Supplement, 20 mL, 1/Pack | 1 / Pk | 1 / Ea | Corning® | per each |
| 355006 | Corning® MITO+ Serum Extender, 5 mL, 1/Pack | 1 / Pk | 1 / Ea | Corning® | per each |
| 355500 | Corning® Nu-Serum™ Growth Medium Supplement, 500 mL, 1/Pack | 1 / Pk | 1 / Ea | Corning® | per each |
| 3.56E+05 | Corning® Nu-Serum™ IV Growth Medium Supplement, 500 mL, 1/Pack | 1 / Pk | 1 / Ea | Corning® | per each |
| 356006 | Corning® Endothelial Cell Growth Supplement (ECGS), 100 mg, 1/Pack | 1 / Pk | 1 / Ea | Corning® | per each |
| 356123 | Corning® Bovine Pituitary Extract (BPE), 75mg, 15mg/Container, 5/Pack | 1 / Pk | 1 / Ea | Corning® | per each |
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