Buchiglas – Process equipment > 250 liter
Glass-lined steel reactors from 250 to 10000 liter combined with customized glass distillation and rectification systems (glass distillation overheads) for commercial chemical manufacturing. Separation & rectification (glass) columns and stationary gas scrubbers complete the process equipment offering. Built from borosilicate glass 3.3, glass-lined steel, fluoropolymers and Hastelloy® and tailored according to your process requirements. Highly corrosion resistant heat exchangers made of high-performance materials guarantee stable process conditions and a long service life. Full compliance with cGMP requirements and regulations such as ATEX and PED.
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Available Models
Customized process reactor systems for demanding pharmaceutical and chemical applications up to 10’000 liters
Buchiglas specializes in engineering and building of complete reaction systems for production scales ranging from 250 to 10’000 liters.
Technical Specifications
- Glass-lined steel reactor: 250 – 10’000 liter
- Pressure: -1.0 (FV) to +0.5 bar
- Temperature: -60 °C (-90 °C) to +200 °C
- Material: Borosilicate glass 3.3, glass-lined steel, PTFE, PFA, Hastelloy®, tantalum
Key features & advantages of production systems:
- Full customization – Customized process plants through the integration of diverse functionalities, including dosing pumps and weighing systems, ensuring that the systems are optimized for the specific process requirements.
- Flexible piping – Built with our proprietary buchiflex glass piping system (DN15 – DN150) for flexible, stress-free piping connections and quick changes with short downtimes due to its flexibility.
- Corrosion resistance – Combinations of glass lined steel (or Hastelloy®), borosilicate glass 3.3, fluoropolymers and ceramics guarantee highest levels of corrosion resistance.
- Process visibility – Glass overheads allow visual monitoring of the process, even at production scale – visibility is assurance.
Applications
- Chemical synthesis (organic & inorganic)
- Extraction & evaporation
- Purification & crystallization
- Distillation & reflux distillation
- Azeotropic distillation
- Cryogenic reactions (low temperature chemistry)
- Solvent recovery, recycling & purification
- Acid recovery, recycling & purification
- Active pharmaceutical ingredients (APIs)
- Highly potent active pharmaceutical ingredients (HPAPIs)
- Agrochemicals
- Fine chemicals / Specialty chemicals
- Flavors & fragrances
- Pigments & dyes
- Detergents & tensides
- Coatings, paints & adhesives
- Explosives & propellants
- Electronic chemicals
- Semiconductor chemicals
- Specialty polymers
- Battery chemicals
- Precious Metals
- Catalysts
Efficient thermal separation optimized for production scale
Whether a process requires a solvent recovery or complex multi stage separation, these designed systems provide the corrosion resistance and thermal performance needed for highly demanding chemical environments. The modular glass configurations enable continuous visual process control, helping operators optimize efficiency and monitor hydrodynamics in real time across all production scales.
Typical applications for distillation and rectification systems & columns
- Solvent recovery & purification: Continuous and batch wise recycling of organic and inorganic chemical solvents in multi-purpose plants.
- Acid recovery & concentration: High purity treatment, recycling, and purification of highly corrosive acids.
- API & HPAPI production: Critical purification and synthesis steps in pharmaceutical production plants compliant with cGMP standards.
- Fine & specialty chemicals: High efficiency rectification for high purity chemical processing, agrochemicals, polymers, flavors, and fragrances.
Exhaust gas neutralization for demanding chemical processes
Stationary gas scrubber (volume scrubbing liquid) : Customized according to process requirements
Stationary gas scrubber (column diameter): DN50 up to DN600
Specifications:
- Pressure: -1.0 (FV) to +0.5 bar
- Temperature exhaust gas: -60 °C to +200 °C
- Temperature scrubbing liquid: 0 °C to +80 °C
- Material: Borosilicate glass 3.3, PTFE, ETFE
Design features for gas scrubbers
- Leak free liquid circulation: Equipped with an ETFE lined, magnetically coupled pump that eliminates mechanical seal leaks and prevents corrosive fluid bypass.
- Precise process control: An integrated reducing valve allows for fine tuning of the scrubbing liquid flow rate to optimize neutralization efficiency.
- Thermal management: A spiral cooler in the liquid circuit keeps the scrubbing fluid within optimal temperature limits during exothermic gas liquid reactions.
Applications
- Off gas and vent gas treatment from the reactor system.
- Absorption and neutralization of toxic, acidic, or caustic chemical vapors (such as HCl, SO₂, Cl₂, or NH₃).
- Stripping processes to remove volatile organic compounds or dissolved gases from liquids.
Excellent heat transfer and visual process control
Efficient thermal management is critical for chemical processes. Buchiglas offers a comprehensive range of heat exchangers, including shell & tube, spiral, and U-shape types. Buchiglas specializes in glass, glass lined, silicon carbide (SiC), Hastelloy®, titanium and tantalum solutions that combine excellent heat transfer properties with high corrosion resistance. These solutions made of high-performance materials are ideal for highly demanding chemical and pharmaceutical processes.
Key Features
- Process visibility: Glass (shell) heat exchangers allow for direct monitoring of the condensation and fluid flow dynamics, enabling efficient process control and optimization. Seeing is believing.
- High performance: Shell & tube exchangers offer excellent thermal conductivity, reducing required surface area. This allows for a minimized footprint while maintaining high corrosion resistance.
- High cleanability: Our heat exchanger solutions are designed for cGMP compliance with maximized drainability and cleanability. Smooth glass surfaces prevent product buildup and simplify cleaning validation. Thanks to the transparency of the glass (shell) the cleaning status can be observed at any time.
- Modular flexibility: Our proprietary buchiflex glass piping system for leak tight, flexible connections cope with any thermal expansion and vibration and allows for effortless maintenance and (re-) configuration of the piping set-up.
- Safety chambers: Optional safety chambers in our shell & tube design heat exchangers allow for immediate leakage detection and higher coolant pressures, ensuring highest levels of safety and operational reliability.
- Material versatility: Our offering of multiple material combinations (glass, glass lined steel, SiC, Hastelloy®, titanium, tantalum, stainless steel) ensure optimal compatibility with your specific chemical process requirements.
Applications
- Chemical synthesis (organic & inorganic)
- Extraction & evaporation
- Purification & crystallization
- Distillation & reflux distillation
- Azeotropic distillation
- Cryogenic reactions (low temperature chemistry)
- Solvent recovery, recycling & purification
- Solvent condensation in drying processes (e.g. filter dryers)
- Acid recovery, recycling & purification
- Active pharmaceutical ingredients (APIs)
- Highly potent active pharmaceutical ingredients (HPAPIs)
- Agrochemicals
- Fine chemicals / Specialty chemicals
- Flavors & fragrances
- Pigments & dyes
- Detergents & tensides
- Coatings, paints & adhesives
- Explosives & propellants
- Electronic chemicals
- Semiconductor chemicals
- Specialty polymers
- Battery chemicals
- Precious metals
- Catalysts
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Buchiglas is a Swiss engineering and manufacturing company specializing in reactor systems, pilot plants, and process equipment for the chemical,…
