Biochrom – Amino Acid Analyzer – 30+ Series
Amino acid analysis is a technique based on ion exchange liquid chromatography, used in a wide range of application areas to provide qualitative and quantitative compositional analysis.
It is a key part of the ICH Q6B guidelines for characterization of biopharmaceuticals.
Technical Specifications
| Detection System | Nninhydrin – post column derivatization |
| Reproducibility | Area: Better than 0.5% RSD at 10 nanomoles. Retention time: Better than 0.1%RSD |
| Pumps | Two dual piston pumps with integrated pressure transducer and drain valve. Ceramic pump head, sapphire pistons and valves. Electronically controlled piston wash. |
| Operating Pressures | Buffer pressure: maximum 150 bar. Ninhydrin pressure: maximum 24 bar |
| Analytical Column | High pressure PEEK column packed with Ultropac 8 cation exchange resin. Peltier heating/cooling system. |
| Sample Injection | 3 injection modes (full loop, partial loop and micro), 84 position autosampler. Sample volumes from 1μL to 5000μL. 200μL loop supplied as standard. |
| Temperatures | Column temperature variable between 20°C and 99°C. Reaction Coil temperature adjustable between 40°C and 145°C (135°C is optimum). |
| Software | BioSys v3.0 control software Biochrom Alias Manager autosampler control software Latest version of EZChrom Elite Data Handling 21 CFR part 11 compliant |
| Photometer | Single flow cell with optical beam splitter with detection at 440nm and 570nm |
| Weight and dimensions | Bench top Fluidics Cabinet: 50kg/110lbs, 48 x 59 x 57cm /19 x 23 x 22 inches Autosampler: 21kg/46lbs, 30 x 57.5 x 36cm /12 x 23 x 14in (cooled version) 19kg/42lbs, 30 x 51 x 36cm/12 x 20 x 14in (ambient version) |
| Required Services | Oxygen free Nitrogen gas (99.99%) or Argon gas regulated to 5 bar. Drainage facility. 240V/100V, 50Hz/60Hz, 300VA mains supply. |
| Safety Systems | Automatic shut-down and reaction coil flushing in the event of: Power failure Photometer lamp failure Low ninhydrin, buffer, coil and nitrogen pressures High coil and column temperatures, high ninhydrin, buffer and coil pressures. |
Available Models
Key Features
- Accurate:
Superb separation, accurately identifies and quantifies free amino acids, as well as the amino acid composition of proteins and peptides. - Reliable:
Minimal matrix interference and near baseline separation helps to reduce ambiguities in interpretation and increase confidence in diagnosis of inborn errors of metabolism. Automated derivatization of amino acids maximizes reproducibility. - Fast:
Rapid protocols that increase sample throughput by cutting analysis time. - Economical:
The column cleaning and repacking service, gives columns an almost indefinite life and cuts the cost of ownership. - Fully Automated:
Total PC control allows 24/7 operations. - Versatile:
Wide variety of sample types compatible: Urine, plasma, serum, CSF, amniotic fluid, culture media, tissue extracts, protein hydrolysates from various food and feedstuff samples or synthetic drugs, nutraceuticals, beverages. - Easy to implement:
No lengthy method development required as this well characterized system is established worldwide. All customers have their instrument optimised to their application directly from the factory. - Convenient:
Interchangeable sample trays allow samples to be prepared in advance and stored refrigerated. - Robust:
Advanced fluidics and robust hardware mean easy maintenance for users, backed by the reassurance of Biochrom’s dedicated service and support team. - Flexible:
Integrated software, choice of different methods to adapt to the user’s needs. Automatic sample set-up. Networking and exporting of data. - Compact:
Bench top design requiring minimum lab space.
Biochrom 30 Amino Acid Analyzer
Key Industries
- Aerospace
- Agriculture
- Automotive
- Biopharmaceutical and Biotechnology
- Chemical
- Construction
- Cosmetics & Personal Care
- Defense
- Die & Mould
- Education & Academics
- Electronics
- Energy
- Environmental
- Food & Beverage
- Luxury
- Machinery & Manufacturing
- Medical
- Mining & Minerals
- Oil & Gas
- Optical
- Paper & Wood
- Pharmaceutical
- Polymers, Plastics and Rubbers
- Powders & Pigments / Coating
- Railway
- Semiconductor, Solar & Electronics
- Service
- Textile
- Wholesale & Retail
Biochrom has a long history of making quality scientific instruments for a wide range of applications in the clinical, life-science…
