A chambered coverslip with 8 wells for cell culture, immunofluorescence, and high-end microscopy

Investigate chemotaxis of fast or slow migrating adherent cells and non-adherent cells in 2D or 3D gel matrices

Product Outline:

• A µ-Slide with a porous glass membrane for transmigration and transport studies under both static and flow conditions
• Brilliant optical quality through the thin, porous glass membrane
• Full access to the apical and basal sides of adherent cells in numerous applications
• Different pore sizes available for various cell types
• Suitable for the establishment of lung models with air-liquid interface (ALI)

Applications

• Trans-endothelial migration under flow conditions
• Co-cultivation of cell layers and transport in 2D or in a 3D gel matrix
• Apical-basal cell polarity assays
• Skin and lung models with liquid-air interface
• Cell barrier model assays with apical-basal gradients
• Cell migration assays based on filters and porous membranes

Nanoscale Imaging Has Never Been Easier

Collect nanoscale topography data on your benchtop in three clicks with the nGauge AFM.

ICSPI has integrated all of the components of a traditional AFM onto a single 1 mm x 1 mm chip to create the world’s first single-chip AFM. That means that 250 AFMs can fit on the face of a penny.

The nGauge AFM uses micro-electro-mechanical systems (MEMS) to control the X, Y and Z position of the tip. This means that no alignment of lasers is required.

The nGauge is the smallest AFM in the world. Because the entire unit weighs less than 500 grams, the nGauge rejects building vibrations, so no vibration isolation table is needed, which makes the nGauge a true benchtop AFM.

What can I use AFM for?

AFM provides topographical data of a surface. That means that you can look at the shape and size of individual features, such as the pits on a DVD, or look at the particle density, such as the number of nanoparticles in an area.

The nGauge AFM can be used to investigate surfaces where the features are up to 10 µm tall. It’s tricky to pinpoint a lower limit, but the RMS noise in the vertical (z) direction of the nGauge is 1 nanometre (nm). So, depending on your requirements, features as small as 5–10 nm can be imaged with the nGauge with acceptable accuracy.

To put what a nanometer is into perspective, a quarter (25-cent coin) is about 2 cm wide. An E. coli bacterium cell is 2 µm wide (10,000× smaller than a quarter). And the diameter of a DNA helix is 2 nm (1,000× smaller than a bacterium).

Product information:

• Made from high grade gamma resistance polystyrene
• The culture device with monolayer or up to 10 layers can realize large-scale cell culture by one time
• Easy to use and standardized operation ensures uniform cell growth
• Suitable for most adherent cell lines
• Linear amplification, easy to expand to the industrial scale
• Transparent material can be observed directly under a microscope
• Modular design can be multi-level series or parallel
• It can be equipped with a variety of online monitoring instruments
• Strict integrity tested
• Sterilized by gamma irradiation
• DNase/RNase-free & Non-pyrogenic

The Allegro™ Peristaltic Pump family is engineered for worldwide regulatory compliance. The outstanding durability and quality of this advanced peristaltic system is second to none.

Pre-Packaged Solutions for Industry

In nearly four decades of serving customers across many industries, LabVantage has learned what it takes to deliver the functionality and workflows those customers need, and want. But instead of continuing costly, risk-prone customizations, we’ve packaged that knowledge into industry-specific versions of LabVantage LIMS to speed deployment, without sacrificing functionality.