Quantabio extraction reagents provide a simplified and cost-effective alternative to traditional nucleic acid (NA) purification methods and are optimized to work in series with Quantabio ToughMix reagents.

Innovation at Your Fingertips

RedShiftBio’s AQS³pro overcomes many of the limitations of traditional spectroscopy-based technologies with ultrasensitive, highly reproducible, automated structural measurements of proteins and other biomolecules. It can be used for a wide range of applications from formulation development of mAb-based biotherapeutics to robust measurements of ADCs, AAVs, and mRNA. Powered by Microfluidic Modulation Spectroscopy (MMS), the AQS³pro is designed to provide five key measurements— aggregation, quantitation, stability, similarity, structure—directly supports biomolecule characterization throughout the biopharmaceutical development pipeline.

Key features:

• Ability to measure wide range of native sample concentrations from <0.1 mg/ml to >200 mg/ml
• Fully automated sample-handling, with both 24 and 96 well plate formats
• Real-time background subtraction eliminates need to dialyze samples
• Detection of <2% change in secondary structure even at low concentrations
• Advanced onboard data analytics enabling rapid and robust data interpretation and reporting

Ideal for the range of 1.5 to 2,600 µm. They are autoclavable and therefore suited for CIP (cleaning in place) and SIP (sterilization in place).

Individual customization possibilities for your process’s needs

• Length
• Pressure resistance
• Temperature
• Material

For corrosive mediums, the parts of the system that come into contact can be fashioned out of C22 Hastelloy or titanium. The SOPAT stick probes are mesoscopic incident light probes and can be equipped with a U-Light as a transmission probe if desired.

Application examples for particle analysis with the SOPAT Mesoscopic probes

• Emulsions
• Chocolate
• Grinding processes such as ball mills
• Fluid bed granulation
• Spray drying
• Polymerization
• Crystallization
• Dispersion

Offering the highest throughput of our entire DVS range, the DVS Endeavour precisely controls and measures temperature and relative humidity while simultaneously recording the highest resolution changes in mass on up to 5 samples simultaneously.

Combined with a range of modular accessories, the DVS Endeavour is one of the most versatile DVS instruments on the market.

The iGC-SEA continues Surface Measurement Systems’ pioneering history with inverse gas chromatography (iGC), which now spans more than fifteen years.

The iGC-SEA is a second generation iGC instrument. It is the world’s only commercial instrument based on the iGC principle. The unique SMS injection scheme provides a wide range of injection concentrations with unrivalled accuracy and reproducibility.

How Does the iGC-SEA Work?

The iGC-SEA is based on Inverse Gas Chromatography (iGC) methodology and is a gas phase technique for characterising surface and bulk properties of solid materials. The principles of IGC are very simple, being the reverse of a conventional gas chromatographic (GC) experiment.A cylindrical column is uniformly packed with the solid material of interest, typically a powder, fibre or film. A pulse of constant concentration of gas is then injected down the column at a fixed carrier gas flow rate, and the time taken for the pulse or concentration front to elute down the column is measured by a detector. A series of iGC measurements with different gas phase probe molecules then allows access to a wide range of phyisco-chemical properties of the solid sample.

The injected gas molecules passing over the material adsorb on the surface with a partition coefficient KS:

Ks = Vn / Ws

Where VN is the net retention volume – the volume of carrier gas required to elute the injection through the column, and WS is the mass of the sample. VN is a measure of how strongly the probe gas interacts with the solid sample and is the fundamental data obtained from an IGC experiment; from it a wide range of surface and bulk properties can be calculated.

This carbon dioxide (CO2) and oxygen (O2) headspace analyzer provides consistently reliable results and simplicity in operation allowing you to maximise your production efficiency. Its large buttons and clear display ensures testing is simple, errors are eliminated and no special operator training is required.

Numerous packs can be tested quickly with just one button press, saving time and making Quality Assurance more efficient. These MAP analyzers can test all pack sizes and very low volumes.

Rigid cans and jars can also be tested using the simple-to-use can piercing station which supports the cans and jars for accurate analysis using a standard needle probe. A 45° Adaptor is also available to aid measurement of small volumes of headspace.

There are a variety of ways to perform analysis; Timed Tests, AutoSense, Peak/Valley, Syringe Direct Injection or Continuous Testing. Fast configuration and selection provides the test method which is best for you. Easy to see Pass and Fail messages speeds up the analysis process and removes any uncertainty with interpreting measurements.

The Gaspace Data Manager software allows you to download results stored on your gas analyzer and upload new settings. You can also search through your stored data by time, date, user, production line or any of the product information.